ANERGY Meaning and
Definition
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Anergy refers to a state of immunological unresponsiveness or hypoactivity occurring in the immune system. It is characterized by the inability of the immune cells, especially T cells, to mount an appropriate response against foreign antigens or pathogenic stimuli. In this state, the immune cells fail to produce a robust immune response, leading to a weakened defense mechanism against invading pathogens and antigens.
Anergy can be induced by various factors, including chronic exposure to an antigen, lack of co-stimulatory signals required for T cell activation, or the presence of inhibitory factors or immunosuppressive environments. When anergy occurs, the immune cells do not proliferate, differentiate, or produce effector molecules like cytokines. Consequently, the immune system fails to eliminate the triggering antigen or pathogen, resulting in potential immune dysregulation and susceptibility to infections or chronic diseases.
The concept of anergy is significant in understanding immune tolerance and autoimmunity. It reflects a mechanism by which the immune system regulates its response to self-antigens to prevent autoimmune reactions. Anergy plays a crucial role in maintaining self-tolerance by suppressing autoreactive T cells that may cause damage to the body's own tissues.
In summary, anergy is a state of diminished immune response characterized by immunological unresponsiveness or hypoactivity. It is an important aspect of immune regulation, contributing to immune tolerance and preventing self-reactivity. Understanding anergy is significant for elucidating various immune-related disorders and developing therapeutic interventions.
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A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for ANERGY
- znergy
- snergy
- wnergy
- qnergy
- abergy
- amergy
- ajergy
- ahergy
- anwrgy
- ansrgy
- andrgy
- anrrgy
- an4rgy
- an3rgy
- aneegy
- anedgy
- anefgy
- anetgy
- ane5gy
Etymology of ANERGY
The word "anergy" is a medical term that was coined in the late 1960s. It is derived from the Greek roots "an-" meaning "without" or "not", and "-ergy" which is derived from "ergon" meaning "work" or "action".
In the context of medicine and immunology, "anergy" refers to a state of immunological unresponsiveness or lack of immune response to an antigen or stimulus that would normally elicit a response. This term is commonly used to describe a condition in which the immune system fails to respond adequately, leading to a decreased or absent immune response.
Similar spelling words for ANERGY
- low-energy,
- energia,
- energy-efficiency,
- lowest-energy,
- renewable-energy,
- ANRJ,
- energy-storage,
- high-energy,
- energy-saving,
- energy-releasing,
- energy-giving,
- zero-energy,
- energy-producing,
- energy-related,
- energy-hungry,
- waste-to-energy,
- Enridge,
- alternative-energy,
- energiya,
- green-energy,
- energy-conservation,
- bio-energy,
- Anergia,
- energy-consuming,
- energy-storing,
- luch-energiya,
- energy-rich,
- wind-energy,
- solar-energy,
- energy-sapping,
- energy-absorbing,
- energy-use,
- energie,
- energy-intensive,
- energeia,
- nuclear-energy,
- energy-based,
- quasi-energy,
- directed-energy,
- higher-energy,
- highest-energy,
- free-energy,
- energy-trading,
- enrage,
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- http://www.energy.gov,
- energy-efficient,
- non-energy,
- anorak,
- binding-energy,
- energy,
- energi,
- anuric,
- mass-energy,
- ENRGE,
- atomic-energy,
- enargia,
- energy-boosting,
- enerji,
- lower-energy,
- energy-momentum,
- clean-energy,
- self-energy.
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