AMINOQUINOLINES Meaning and
Definition
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Aminoquinolines are a class of organic compounds that contain both an amino group (-NH2) and a quinoline ring system. Quinoline is a heterocyclic aromatic compound composed of a benzene ring fused to a pyridine ring. Aminoquinolines are commonly used as a class of antimalarial drugs due to their potent antiprotozoal activity against the Plasmodium parasite, which causes malaria.
These compounds are typically synthesized by introducing an amino group at the desired position of a quinoline ring. The presence of the amino group enhances their biological activity by allowing for interactions with specific receptors or enzymes involved in the life cycle of the parasite. Aminoquinolines work by inhibiting the parasite's ability to break down hemoglobin, resulting in the accumulation of toxic heme molecules that ultimately lead to its death.
Besides their antimalarial properties, aminoquinolines have also been investigated for their potential in treating other diseases, such as autoimmune disorders and viral infections. Their diverse chemical structures and pharmacological properties make them promising candidates for developing novel therapeutic agents.
However, like any drugs, aminoquinolines can have side effects, including gastrointestinal disturbances, skin rash, and even more severe complications in some cases. Therefore, their use should be closely monitored and prescribed under medical guidance. Ongoing research and development in the field of aminoquinolines continue to explore their potential for malaria treatment and other therapeutic applications.
Common Misspellings for AMINOQUINOLINES
- zminoquinolines
- sminoquinolines
- wminoquinolines
- qminoquinolines
- aninoquinolines
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- ajinoquinolines
- amunoquinolines
- amjnoquinolines
- amknoquinolines
- amonoquinolines
- am9noquinolines
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- amiboquinolines
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- amijoquinolines
- amihoquinolines
- aminiquinolines
- aminkquinolines
- aminlquinolines
Etymology of AMINOQUINOLINES
The word "aminoquinolines" has its etymology rooted in the combination of two terms, "amino" and "quinoline".
1. Amino: The term "amino" comes from the word "amine", which refers to a type of organic compound that contains a nitrogen atom bonded to one or more carbon atoms. The word "amine" originated from the German term "Ammoniak" (ammonia). It was coined in 1863 by the German chemist August Wilhelm von Hofmann.
2. Quinoline: The term "quinoline" refers to a heterocyclic aromatic compound consisting of a benzene ring fused to a pyridine ring.
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