How Do You Spell AMINOPEPTIDASE M?

Pronunciation: [ɐmˈɪnə͡ʊpptˌɪde͡ɪs ˈɛm] (IPA)

The spelling of "Aminopeptidase M" can be complicated to understand without knowledge of its IPA phonetic transcription. The word is pronounced as "aɪˌmɪnoʊˈpɛptɪdeɪs ɛm". The first syllable is pronounced as "ai," the second as "mi," and the third syllable as "no." The word ends with "peptidase" pronounced as "pep-ti-deys." The letter M is a shorthand for the full name of the enzyme, which is M1 aminopeptidase. With this pronunciation guide, the spelling and correct usage of the word will no longer be confusing.

AMINOPEPTIDASE M Meaning and Definition

1. Aminopeptidase M is an enzyme belonging to the family of metallopeptidases, specifically the class of aminopeptidases. It is also known as aminopeptidase N (APN) or the microsomal aminopeptidase. This enzyme is widely distributed in various tissues and is involved in the breakdown of proteins and peptides.

   The primary function of aminopeptidase M is the removal of amino acids from the amino terminus (N-terminus) of peptide chains. It selectively cleaves neutral and basic amino acids from the terminus of peptides, operating in a sequential manner from the N-terminus towards the C-terminus. Aminopeptidase M plays a critical role in maintaining cellular homeostasis by regulating the levels of peptides and proteins in the body.

   This enzyme demonstrates high affinity for peptides consisting of fewer than 10 amino acids. It has been found to be particularly active in the small intestine and kidney, where it contributes to the digestion and absorption of dietary proteins. Moreover, aminopeptidase M is also involved in the metabolism and inactivation of certain bioactive peptides, such as bradykinin and angiotensin, having implications in cardiovascular and renal function.

   The importance of aminopeptidase M in various physiological processes makes it an interesting target for pharmaceutical research. Inhibitors of aminopeptidase M have been studied as potential drugs for treating hypertension, inflammation, and cancer. Further investigations into the structure, regulation, and therapeutic potential of aminopeptidase M are continuously advancing our understanding of its role in human health and disease.

Common Misspellings for AMINOPEPTIDASE M

• zminopeptidase m
• sminopeptidase m
• wminopeptidase m
• qminopeptidase m
• aninopeptidase m
• akinopeptidase m
• ajinopeptidase m
• amunopeptidase m
• amjnopeptidase m
• amknopeptidase m
• amonopeptidase m
• am9nopeptidase m
• am8nopeptidase m
• amibopeptidase m
• amimopeptidase m
• amijopeptidase m
• amihopeptidase m
• aminipeptidase m
• aminkpeptidase m
• aminlpeptidase m

Etymology of AMINOPEPTIDASE M

The etymology of the word "Aminopeptidase M" can be broken down as follows:

1. Amino - Derived from the Latin word "amīnus", meaning "of ammonia". In biological terminology, it refers to compounds containing an amino group (-NH2).

2. Peptidase - Derived from the Greek word "peptós", which means "digested". It refers to enzymes that break down proteins into smaller peptide fragments by hydrolyzing peptide bonds.

3. M - In this context, "M" likely stands for "Metallopeptidase". It is a classification of peptidases that require metal ions, such as zinc or manganese, to catalyze their enzymatic activity.