AMIDOPYRINE Meaning and
Definition
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Amidopyrine, also known as aminopyrine, is a synthetic compound classified as a pyrazolone derivative. It belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics. Amidopyrine possesses both antipyretic (fever-reducing) and analgesic (pain-relieving) properties, making it commonly employed for the management of pain and inflammatory conditions.
Amidopyrine acts primarily by inhibiting the synthesis of prostaglandins, specifically through the inhibition of the enzyme cyclooxygenase. Prostaglandins are known to mediate pain and inflammation responses in the body. By impeding their production, amidopyrine helps alleviate pain and reduce fever associated with various conditions, such as headaches, toothaches, musculoskeletal pain, and febrile illnesses.
Despite its potency as an analgesic and antipyretic, the usage of amidopyrine has been largely superseded by newer NSAIDs due to concerns about its safety profile. In the past, it has been associated with a rare but severe adverse effect known as agranulocytosis, which involves a dangerous decline in white blood cell count and can lead to severe infections. Consequently, many countries have discontinued or restricted its use, and it is no longer a commonly prescribed medication.
It is noteworthy that amidopyrine may still be found in certain regions, often in combination with other active ingredients in multi-component medications, such as cold and flu medicines or other over-the-counter products. Nevertheless, the overall use of amidopyrine has diminished over time due to the availability of safer and equally effective alternatives.
Common Misspellings for AMIDOPYRINE
- zmidopyrine
- smidopyrine
- wmidopyrine
- qmidopyrine
- anidopyrine
- akidopyrine
- ajidopyrine
- amudopyrine
- amjdopyrine
- amkdopyrine
- amodopyrine
- am9dopyrine
- am8dopyrine
- amisopyrine
- amixopyrine
- amicopyrine
- amifopyrine
- amiropyrine
- amieopyrine
Etymology of AMIDOPYRINE
The word "amidopyrine" originates from a combination of two components: "amido-" and "pyrine".
1. "Amido-" is derived from the chemical compound called "amide". An amide is a compound formed by replacing the hydroxyl group (-OH) of an acid with an amino group (-NH2), resulting in the formation of the amide group (-CONH2). In this case, "amido-" signifies the presence of an amide group in the compound.
2. "Pyrine" is a term derived from the chemical compound "pyrazolone". Pyrazolone is a heterocyclic compound composed of a pyrazole ring fused with a ketone group. It is commonly used as a basis for various pharmaceutical drugs.
Combining these components, "amidopyrine" denotes a compound with an amide group linked to a pyrazolone structure.
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