ALLOTYPIC ANTIBODY Meaning and
Definition
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An allotypic antibody, also known as allotype antibody, refers to a specific type of antibody found in the immune system of an individual, which exhibits distinct differences in its amino acid sequence compared to other individuals. This unique variation arises due to genetic polymorphisms within the genes responsible for coding the antibody molecules.
The term "allotype" refers to the genetic variations present in a population that result in different forms of a particular molecule. In the case of an allotypic antibody, these genetic differences lead to structural disparities in the constant region of the antibody molecule. The constant region is responsible for determining the antibody's effector functions, such as activating immune cells or binding to specific targets.
Allotypic antibodies are produced by B cells, a type of white blood cell, in response to antigens encountered by an individual. These antibodies play a crucial role in the adaptive immune response by recognizing and binding to specific foreign substances, or antigens, such as bacteria, viruses, or toxins. The genetic variations that result in allotypic antibodies are inherited and can be found within a population. They can be detected and characterized using specialized immunological techniques, such as serotyping or genetic sequencing.
Understanding allotypic antibodies is important in various fields of research, including immunogenetics and immunotherapy. It allows scientists to investigate genetic diversity within a population and its implications for immune responses and disease susceptibility. Additionally, allotypic antibodies have been studied as potential therapeutic agents, with the aim of harnessing their unique antigen-binding properties for targeted treatments, such as cancer immunotherapy or precision medicine.
Common Misspellings for ALLOTYPIC ANTIBODY
- zllotypic antibody
- sllotypic antibody
- wllotypic antibody
- qllotypic antibody
- aklotypic antibody
- aplotypic antibody
- aolotypic antibody
- alkotypic antibody
- alpotypic antibody
- alootypic antibody
- allitypic antibody
- allktypic antibody
- allltypic antibody
- allptypic antibody
- all0typic antibody
- all9typic antibody
- allorypic antibody
- allofypic antibody
- allogypic antibody
- alloyypic antibody
Etymology of ALLOTYPIC ANTIBODY
The term "allotypic antibody" is derived from the combination of two words: "allotype" and "antibody".
1. "Allotype" comes from the prefix "allo-" meaning "other" or "different", and the word "type", which refers to a classification or representative category. In biology, an allotype is a variant form of a protein or another molecule that exists within a specific species. Allotypes are determined by genetic differences among individuals of the same species.
2. "Antibody" refers to a specialized protein produced by the immune system in response to foreign substances (antigens) such as bacteria or viruses. Antibodies help in identifying and neutralizing these antigens, thereby protecting the body from infections.
Therefore, "allotypic antibody" refers to an antibody that possesses unique molecular variations (allotypes) within a particular species.
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