ALLOGRAFT IMMUNITY Meaning and
Definition
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Allograft immunity is a term used in the field of immunology to describe the immune response provoked by the introduction of an allograft into an organism. An allograft refers to a tissue or organ transplanted from one individual to another of the same species but with a different genetic makeup. This transplantation can trigger an immune reaction in the recipient, as the body recognizes the transplanted tissue as foreign and attempts to eliminate it.
The immune response mounted against the allograft involves various mechanisms aimed at destroying or rejecting the foreign tissue. These mechanisms include the activation of immune cells, such as T cells and natural killer cells, which recognize the presence of non-self antigens on the allograft. These immune cells initiate an inflammatory response and release cytokines, signaling molecules that further enhance the immune reaction.
Allograft immunity can result in the rejection of the transplanted tissue, leading to graft failure. This rejection can occur through different pathways, including hyperacute, acute, and chronic rejection. Hyperacute rejection is characterized by rapid and severe immune response, usually occurring within minutes to hours after transplantation. Acute rejection involves a cellular immune response that develops over days to weeks, leading to tissue damage. Chronic rejection is a long-term process that can develop months or years after transplantation, involving both immune and non-immune mechanisms.
To mitigate the risk of allograft immunity and improve the success of transplantation, various immunosuppressive strategies are employed. These strategies aim to suppress the recipient's immune response and prevent the rejection of the allograft.
Common Misspellings for ALLOGRAFT IMMUNITY
- zllograft immunity
- sllograft immunity
- wllograft immunity
- qllograft immunity
- aklograft immunity
- aplograft immunity
- aolograft immunity
- alkograft immunity
- alpograft immunity
- aloograft immunity
- alligraft immunity
- allkgraft immunity
- alllgraft immunity
- allpgraft immunity
- all0graft immunity
- all9graft immunity
- allofraft immunity
- allovraft immunity
- allobraft immunity
- allohraft immunity
Etymology of ALLOGRAFT IMMUNITY
The word "allograft immunity" is derived from two main components: "allo-" and "graft immunity".
1. "Allo-" is a prefix derived from the Greek word "állos", meaning "other" or "different". It is commonly used in scientific and medical terminology to refer to other individuals or species, emphasizing the concept of non-self or foreignness.
2. "Graft immunity" refers to the immune response that occurs when tissues or organs from one individual (the donor) are transplanted into another individual (the recipient). In this context, the term "graft" is derived from the verb "graft", which means "to transplant or implant living tissue surgically". "Immunity" refers to the body's ability to defend itself against foreign substances, such as pathogens or transplanted tissues, by activating immune responses.
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