ALLOGENE Meaning and
Definition
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Allogene is a term used in the field of medicine and biology, particularly in the context of organ transplantation and immunology. It refers to a substance or entity that originates from a genetically distinct individual of the same species. Specifically, it pertains to tissues, organs, or cells introduced into an organism from a donor who is not genetically identical to the recipient.
Allogeneic transplantation, also known as allografting, involves the transfer of tissues or organs between two individuals of the same species, usually with the intention of replacing a damaged or nonfunctional organ in the recipient. The term allogene is often used to describe the donor organ or tissue in such cases.
Due to the genetic disparity between the allogeneic donor and recipient, the immune system of the recipient recognizes the allogeneic transplant as foreign and mounts an immune response against it. This immune response can result in rejection of the allograft, where the recipient's immune cells attack and destroy the transplanted tissue or organ.
To prevent or reduce the risk of rejection, various immunosuppressive medications may be administered to the recipient following an allogenic transplant. These medications aim to suppress the recipient's immune response, allowing the transplanted tissue or organ to function adequately in the recipient's body.
Allogeneic transplantation has significantly improved the treatment of various diseases and conditions, offering viable options for patients in need of organ or tissue replacements.
Common Misspellings for ALLOGENE
Etymology of ALLOGENE
The word "allogene" is derived from the combination of two Greek roots: "allo-" and "genea".
1. "Allo-" (αλλο-) is a Greek prefix that means "other" or "different".
2. "Genea" (γένεα) is a Greek term that translates to "kind" or "race".
When these two elements are combined, "allogene" refers to something that is "of a different kind" or "of a different race".
