The spelling of "alkaline tuberculin" can be confusing due to its complex pronunciation. In IPA phonetic transcription, it is pronounced as /ˈælkəlaɪn tuːbərkjʊlɪn/. The word begins with the stress on the first syllable "al-", followed by the "k" sound and the long "a" sound. The second word, "tuberculin", features a stress on the second syllable with a "b" and a short "u" sound. The final syllable, "-in", is pronounced with the "ih" as in "bit" sound. Proper spelling and pronunciation are key to clear communication in medical contexts.
Alkaline tuberculin refers to a type of tuberculin used in the diagnosis of tuberculosis (TB) infection. Tuberculin is a sterile protein derivative derived from the bacterium Mycobacterium tuberculosis, which is the causative agent of tuberculosis.
Alkaline tuberculin is prepared by treating the purified protein derivative (PPD) of M. tuberculosis with an alkaline solution. This process alters the chemical properties and characteristics of the tuberculin, rendering it more soluble and improving its stability. The alkaline treatment allows for longer storage of the tuberculin without compromising its effectiveness in diagnosing tuberculosis.
The use of alkaline tuberculin involves an intradermal skin test known as the tuberculin skin test or Mantoux test. During this test, a small amount of alkaline tuberculin solution is injected just below the skin surface of the forearm. After 48-72 hours, the injection site is examined for a localized reaction, known as a delayed-type hypersensitivity response. The presence of a raised, red bump at the injection site indicates exposure to tuberculin protein and the possibility of TB infection.
Alkaline tuberculin, along with other tuberculin preparations, plays a crucial role in the detection and surveillance of tuberculosis. This diagnostic tool helps identify individuals who have been exposed to Mycobacterium tuberculosis, allowing for early detection, adequate treatment, and prevention of the spread of the disease.
TA, an extract of triturated tubercle bacilli, obtained by treatment with a decinormal solution of caustic soda.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "alkaline" comes from the Arabic word "qali" and the Latin word "alkali", which refer to a type of mineral substance that is soluble in water and has basic properties. The term "tuberculin" is derived from the Latin word "tuberculum", meaning a small swelling or protuberance, often associated with a tuber or nodule caused by infection or disease.
The term "alkaline tuberculin" combines these two words to describe a substance that has alkaline properties and is related to or derived from tuberculin. It is often used in the context of medical or diagnostic procedures related to tuberculosis or other similar diseases.