How Do You Spell AGOUTI GENE?

Pronunciation: [ˈaɡa͡ʊtˌi d͡ʒˈiːn] (IPA)

The agouti gene is a gene found in many animals, including rodents, cats, and humans. It is responsible for regulating the production of melanin, which determines the color of an animal's fur or hair. The spelling of "agouti gene" is pronounced as /əˈɡuːti dʒiːn/ in IPA phonetic transcription. The word "agouti" comes from the Tupi language of South America, where it originally referred to a type of rodent with a similar coloring to that produced by the agouti gene.

AGOUTI GENE Meaning and Definition

1. The agouti gene is a specific gene found in many mammals, including humans, that plays a crucial role in determining hair color and pigmentation. It is named after the agouti, a rodent species known for its characteristic banded coat coloration, which is caused by variations in this gene.

   The agouti gene controls the production of a protein called agouti-signaling protein (ASP). This protein acts as a signaling molecule in the development of hair follicles. In its normal functioning state, the agouti gene regulates the switching on and off of pigmentation in the hair. This results in the production of eumelanin, which is responsible for darker colors, and pheomelanin, which produces lighter colors.

   However, mutations or variations in the agouti gene can lead to abnormal hair pigmentation. For example, if the agouti gene is overexpressed, it can disrupt the proper regulation of pigmentation and result in a phenotypic characteristic known as "agouti coat color." This coat color consists of alternating bands of dark and light hair, similar to that observed in agouti rodents.

   The agouti gene is also associated with variations in hair color in humans. Certain variations in the agouti gene have been linked to lighter hair colors, such as blond or red hair, while other variations are associated with darker hair colors, such as brown or black hair.

   In summary, the agouti gene is a critically important gene that influences hair pigmentation and coloration in many mammalian species, including humans. Its normal expression ensures the proper regulation of hair pigmentation, while variations or mutations can lead to unique coat colors or hair pigmentation patterns.

Etymology of AGOUTI GENE

The word "agouti" comes from the French word "agouti", which originally referred to a Central and South American rodent species known for its speckled or mottled brown fur. The term was then adopted in genetics to describe a specific gene that controls the distribution of pigmentation in mammals. The gene was named after the agouti rodent due to its involvement in determining the coat color patterns observed in the agouti species.