How Do You Spell AFFIMER?

Pronunciation: [ɐfˈɪmə] (IPA)

The spelling of the word "affimer" is based on the French word "affirmer", meaning to affirm or assert. The pronunciation is [af-i-mur], with the stress on the second syllable. The IPA phonetic transcription reflects the sounds of the word: [ɑ] for the "a" sound, [f] for the "f" sound, [ɪ] for the short "i" sound, [m] for the "m" sound, and [ʌr] for the "er" sound. The spelling has been adjusted to accommodate English pronunciation, but the origin of the word is still evident.

AFFIMER Meaning and Definition

1. Affimer is a term that refers to a synthetic protein, designed and engineered to bind to specific target molecules or proteins. Affimers are small, robust molecules that possess high specificity and affinity towards their respective targets. They are derived from Affibody molecules, which are based on a small protein domain, typically derived from a naturally occurring scaffold, such as the human scaffold protein, staphylococcal protein A (SpA).

   Affimers have been developed as an alternative to antibodies, offering greater versatility and potential advantages in certain applications. They can be generated against a wide array of target molecules, ranging from small molecules to proteins and even complex cellular structures, allowing for diverse applications in research, diagnostics, and therapeutics. Meticulous design and modification have enabled the production of these affinity reagents, ensuring high stability, solubility, and target specificity.

   One notable advantage of affimers over antibodies is their ease of engineering, which enables rapid production and optimization. This makes them particularly suitable for numerous applications, including labelling and imaging of cellular targets, drug delivery systems, and diagnostic assays. Furthermore, the smaller size and simplicity of affimer molecules allow for easier manipulation and modification, facilitating their incorporation into various research and clinical methodologies.

   Overall, affimers are a promising class of synthetic proteins that offer great potential in various fields, providing a highly customizable and versatile tool for molecular recognition and targeting purposes, ultimately helping to advance the understanding and treatment of many diseases.

Common Misspellings for AFFIMER

• affier
• zffimer
• sffimer
• wffimer
• qffimer
• acfimer
• avfimer
• agfimer
• atfimer
• arfimer
• afcimer
• afvimer
• afgimer
• aftimer
• afrimer
• affumer
• affjmer
• affkmer
• affomer
• aff9mer

Etymology of AFFIMER

The word "affimer" does not have an established etymology. This is because "affimer" is a relatively new term coined within the field of molecular biology. It is a combination of the words "affinity" and "molecule". In this context, an "affimer" refers to a small protein, usually derived from a human scaffold, that is designed to bind to specific molecular targets with high affinity. The term was developed in the early 2000s by Avacta Group plc, a biotechnology company specializing in this technology.