ADHESION PLAQUE Meaning and
Definition
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The term "adhesion plaque" is a medical and scientific term used to describe a specific structure that plays a crucial role in cellular adhesion and migration processes. An adhesion plaque refers to a specialized complex found within cells, particularly in epithelial and endothelial cells, that mediates the attachment and communication between adjacent cells and the underlying extracellular matrix.
Consisting of various proteins, adhesion plaques act as a bridge between the cell membrane and the extracellular matrix, providing structural integrity, stability, and support to tissues. They play a crucial role in cell signaling, as they transmit mechanical and chemical signals between cells, thus regulating processes like cell growth, differentiation, and migration.
Adhesion plaques typically comprise transmembrane proteins, such as integrins, that interact with extracellular matrix components like collagen and fibronectin, as well as cytoplasmic adapter proteins, including vinculin, talin, and α-actinin. These proteins facilitate the formation of stable adhesive contacts with neighboring cells and the extracellular matrix, allowing cells to adhere to their surroundings and actively interact with their environment.
The formation and function of adhesion plaques are vital for tissue development, maintenance, and repair, as well as for physiological processes such as wound healing, embryogenesis, and immune response. Dysregulation or abnormalities of adhesion plaques have been implicated in various pathological conditions, including cancer metastasis, autoimmune diseases, and tissue degeneration. A thorough understanding of adhesion plaques and their components is crucial for uncovering the mechanisms underlying these diseases and developing potential therapeutic interventions.
Common Misspellings for ADHESION PLAQUE
- zdhesion plaque
- sdhesion plaque
- wdhesion plaque
- qdhesion plaque
- ashesion plaque
- axhesion plaque
- achesion plaque
- afhesion plaque
- arhesion plaque
- aehesion plaque
- adgesion plaque
- adbesion plaque
- adnesion plaque
- adjesion plaque
- aduesion plaque
- adyesion plaque
- adhwsion plaque
- adhssion plaque
- adhdsion plaque
- adhrsion plaque
Etymology of ADHESION PLAQUE
The word "adhesion plaque" is a combination of two terms: "adhesion" and "plaque".
"Adhesion" originates from the Latin word "adhaesio", which means "a sticking or adherence". The word was derived from the verb "adhaerere", meaning "to stick to" or "to adhere". It can be further traced back to the prefix "ad-" (meaning "to" or "towards") and the root "haerere" (meaning "to stick").
"Plaque", on the other hand, comes from the Middle Dutch word "placke", meaning "a metal plate". This term was later borrowed into English and gained more specific meanings, such as "a flat, thin plate" or "an ornamental tablet or plate".
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