How Do You Spell ACTIVATED FACTOR XIII?

Pronunciation: [ˈaktɪvˌe͡ɪtɪd fˈaktə ɹˌə͡ʊmən θˈɜːtiːn] (IPA)

The spelling of the word "Activated Factor XIII" can be explained using IPA phonetic transcription. The word is pronounced as /ˌæktɪˈveɪtɪd ˈfæktər ˈθɜːtiːn/ with stress on the second syllable of "activated" and the first syllable of "factor." The "xiii" in the word stands for the Roman numeral "thirteen." This protein is crucial in clot formation and is activated by thrombin. Overall, understanding the correct spelling and pronunciation of "Activated Factor XIII" is important in medical terminology and communication.

ACTIVATED FACTOR XIII Meaning and Definition

1. Activated Factor XIII, also known as Factor XIIIa, refers to a specific form of the Factor XIII protein found in the blood. Factor XIII is an essential component of the coagulation cascade, which is responsible for forming blood clots to prevent excessive bleeding.

   Activated Factor XIII is generated through the enzymatic cleavage of Factor XIII by thrombin, a key molecule in the coagulation process. Once activated, Factor XIIIa plays a crucial role in stabilizing blood clots, allowing them to endure and provide efficient hemostasis. This protein works by cross-linking fibrin molecules, which are the primary structural component of blood clots, making the clot stronger and more resistant to premature breakdown or dissolution.

   The activation of Factor XIIIa not only strengthens the fibrin network but also ensures the proper maturation of the blood clot. This mechanism aids in the long-term durability of the clot, enabling it to withstand mechanical stress and preserving its stability until the injured tissue has healed.

   Deficiencies in Factor XIII or its activation can lead to a rare bleeding disorder called congenital Factor XIII deficiency. This disorder is characterized by impaired wound healing, recurrent bleeding episodes, and increased susceptibility to spontaneous miscarriages in affected individuals. Treatment for Factor XIII deficiency often involves the administration of activated Factor XIII concentrate to restore normal clot formation and prevent bleeding complications.

Common Misspellings for ACTIVATED FACTOR XIII

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