How Do You Spell ACROCEPHALOSYNDACTYLIA?

Pronunciation: [ˌakɹə͡ʊsfˌaləsˌɪndɐktˈɪli͡ə] (IPA)

Acrocephalosyndactylia is a rare congenital disorder characterized by the fusion of skull bones, typically at the top of the head, and abnormal fusion of fingers or toes. The word is quite lengthy and complicated to spell, but it can be broken down phonetically using IPA transcription- /ˌækrəʊˌsɛfələʊˌsɪndækˈtɪliə/. The word is derived from the Greek words akros (extremity), kephalē (head), syndactylos (finger or toe joined with another), and -ia (condition). The accurate spelling of this word is important in medical contexts to ensure clarity and accuracy for diagnosis and treatment.

ACROCEPHALOSYNDACTYLIA Meaning and Definition

1. Acrocephalosyndactylia is a medical condition characterized by the fusion (syndactyly) of certain fingers or toes, as well as the abnormal shape (acrocephaly) of the head. Acrocephalosyndactylia, also known as Apert syndrome, is a congenital disorder caused by a mutation in the FGFR2 gene, which plays a crucial role in bone and tissue development during prenatal development.

   Individuals with acrocephalosyndactylia typically present with various skeletal abnormalities, including the premature fusion of certain skull bones, resulting in a disproportionately tall and cone-shaped head. This cranial malformation can potentially lead to a range of neurological complications, such as increased intracranial pressure. The fingers and toes are often fused together, particularly the second, third, and fourth digits, which may result in decreased dexterity and mobility. Additionally, other physical abnormalities may be present, including a high arched palate, wide-set eyes, and an underdeveloped mid-face.

   The severity of acrocephalosyndactylia can vary widely among affected individuals. Early diagnosis and intervention are crucial in managing the condition, as treatment often involves a multidisciplinary approach, including surgical interventions to separate the fused fingers and toes, as well as procedures to correct craniofacial abnormalities. Other supportive measures, such as physical and occupational therapy, are essential for optimizing functional abilities and addressing any additional medical or developmental concerns that may arise.

   In summary, acrocephalosyndactylia is a genetic disorder characterized by the fusion of certain digits (syndactyly) and abnormal head shape (acrocephaly). It requires a comprehensive treatment approach to address the various skeletal and

Common Misspellings for ACROCEPHALOSYNDACTYLIA

• zcrocephalosyndactylia
• scrocephalosyndactylia
• wcrocephalosyndactylia
• qcrocephalosyndactylia
• axrocephalosyndactylia
• avrocephalosyndactylia
• afrocephalosyndactylia
• adrocephalosyndactylia
• aceocephalosyndactylia
• acdocephalosyndactylia
• acfocephalosyndactylia
• actocephalosyndactylia
• ac5ocephalosyndactylia
• ac4ocephalosyndactylia
• acricephalosyndactylia
• acrkcephalosyndactylia
• acrlcephalosyndactylia
• acrpcephalosyndactylia
• acr0cephalosyndactylia
• acr9cephalosyndactylia

Etymology of ACROCEPHALOSYNDACTYLIA

The word "Acrocephalosyndactylia" is derived from several Greek roots. "Acro-" comes from the Greek word "akros", meaning extreme or high. "Cephalo-" is derived from the Greek word "kephalē", which means head. "Syndactylia" is composed of "syn", meaning together, and "dactylos", meaning finger. Therefore, "Acrocephalosyndactylia" is a medical term that combines these roots to describe a condition characterized by fusion of the fingers or toes and abnormal head shape.