The word "acroasphyxia" is spelled with an "a" in the first syllable instead of an "o," which may be surprising given its similarity to the word "asphyxia." However, the difference in vowel sound is indicated in the International Phonetic Alphabet transcription as /ˌækrəʊˈæsfɪk.siə/, where the "a" is pronounced as in "cat" and the "o" is pronounced as in "go." The word refers to a condition of impaired blood flow to the extremities, often caused by cold temperatures, and can be deadly if left untreated.
Raynaud's disease.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.