How Do You Spell ACONITINE?

Pronunciation: [ˈakənˌɪtiːn] (IPA)

The word "aconitine" is a chemical compound found in the poisonous plant, Aconitum. Its spelling can be explained using the International Phonetic Alphabet (IPA) transcription. The first syllable, "ac", is pronounced /ˈæk/, rhyming with "back". The second syllable, "o", is pronounced /ˈoʊ/, like the word "oh". The third syllable, "ni", is pronounced /ˈnaɪ/, like the word "nye" (as in "Benny"). The final syllable, "tine", is pronounced /ˈtaɪn/, rhyming with "fine". Overall, the correct pronunciation of "aconitine" is /ˈæk.oʊ.naɪ.tine/.

ACONITINE Meaning and Definition

1. Aconitine is a highly toxic alkaloid compound that is derived from the plant genus Aconitum, commonly known as monkshood or wolfsbane. It is classified as a neurotoxin due to its potent effects on the nervous system.

   Chemically, aconitine is a bicyclic diterpene ester alkaloid with a molecular formula of C34H47NO11. It is typically found in the roots and leaves of Aconitum plants and is known for its characteristic bitter taste. Aconitine possesses a complex structure consisting of a tetracyclic core with various hydroxyl, methoxy, and acetyl groups.

   Aconitine acts by selectively binding to and activating voltage-gated sodium channels in nerve cells. This action leads to the disruption of normal electrical signaling and the excessive release of neurotransmitters, ultimately resulting in paralysis and potentially fatal cardiac arrhythmias.

   The toxic nature of aconitine makes it unsuitable for medicinal use. However, historically, it has been used as a poison and in traditional Chinese medicine for its analgesic, anti-inflammatory, and diuretic properties. It should be noted that the therapeutic dosages of aconitine are very low, and its use should only be carried out by trained professionals under strict supervision.

   Due to its lethal potential, aconitine is also used in scientific research as a tool for studying ion channels and drug development. It serves as a valuable model for understanding the mechanisms of action and the physiological effects that arise from the disruption of sodium channels.

2. The alkaloid of aconite.

   Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.

Common Misspellings for ACONITINE

• zconitine
• sconitine
• wconitine
• qconitine
• axonitine
• avonitine
• afonitine
• adonitine
• acinitine
• acknitine
• aclnitine
• acpnitine
• ac0nitine
• ac9nitine
• acobitine
• acomitine
• acojitine
• acohitine
• aconutine

Etymology of ACONITINE

The word "aconitine" originates from the plant genus Aconitum, commonly known as aconite or monkshood. Aconitum plants are known for their beautiful flowers and poisonous nature. The term "aconitine" specifically refers to a neurotoxic alkaloid found in these plants.

The word "aconite" is derived from the ancient Greek word "ākónīton", which means "a dart tipped with poison" or "arrow poison". This reflects the historical use of aconite plants for poisoning weapons in warfare and hunting.

Over time, the Latin word "aconitum" emerged and was ultimately adopted into English as "aconite". "Aconitine" then developed as a derivative term, specifically referring to the toxic compound found within aconite plants.

Plural form of ACONITINE is ACONITINES