How Do You Spell ACONITATE HYDRATASE?

Pronunciation: [akˈɒnɪtˌe͡ɪt hˈa͡ɪdɹɐtˌe͡ɪs] (IPA)

Aconitate hydratase is an enzyme involved in the citric acid cycle. Its spelling may be confusing due to the presence of multiple vowels and consonants. However, using the International Phonetic Alphabet, the word can be broken down into /ə'kɒ.nɪ.teɪt haɪ'dreɪ.teɪz/. The first syllable is pronounced as "uh," followed by the "k" sound. The "o" is pronounced as "ah," while the "i" is pronounced as "ih." The second word starts with "hai" and ends with "tayz." Overall, the phonetic transcription helps in understanding the pronunciation of aconitate hydratase.

ACONITATE HYDRATASE Meaning and Definition

1. Aconitate Hydratase is an enzyme that plays a crucial role in the tricarboxylic acid (TCA) cycle, also known as the citric acid cycle or Krebs cycle. It catalyzes the isomerization of cis-aconitate to isocitrate by the addition of water. This specific reaction occurs during the second step of the TCA cycle.

   Aconitate Hydratase is a metalloenzyme, meaning it requires a metal ion as a cofactor for its proper functioning. Iron (Fe2+) is the most common metal ion associated with this enzyme. The presence of iron helps facilitate the hydration of the cis-aconitate substrate and ensures the efficient conversion to isocitrate.

   The TCA cycle is a fundamental metabolic pathway found in most organisms, including animals, plants, and bacteria. It acts as a central hub for energy production and intermediary metabolism. Aconitate Hydratase's role in the TCA cycle allows for the conversion of cis-aconitate, an unsaturated compound, into isocitrate, which is an important precursor in oxidative phosphorylation and the production of ATP.

   Deficiencies or mutations in the Aconitate Hydratase enzyme can lead to various metabolic disorders and diseases, including aconitase deficiency and iron storage diseases. Understanding the structure and function of Aconitate Hydratase is crucial for unravelling metabolic pathways and developing therapeutic interventions for related disorders.

Common Misspellings for ACONITATE HYDRATASE

• zconitate hydratase
• sconitate hydratase
• wconitate hydratase
• qconitate hydratase
• axonitate hydratase
• avonitate hydratase
• afonitate hydratase
• adonitate hydratase
• acinitate hydratase
• acknitate hydratase
• aclnitate hydratase
• acpnitate hydratase
• ac0nitate hydratase
• ac9nitate hydratase
• acobitate hydratase
• acomitate hydratase
• acojitate hydratase
• acohitate hydratase
• aconutate hydratase
• aconjtate hydratase

Etymology of ACONITATE HYDRATASE

The word "aconitate hydratase" is derived from a combination of Latin and scientific terminology.

1. Aconitate: The term "aconitate" comes from the Latin word "aconitum", which refers to the plant "Aconitum" or "Aconite". Aconite is a genus of flowering plants that includes various species known for their toxic and medicinal properties.

2. Hydratase: The term "hydratase" is derived from the word "hydrate", which comes from the Greek word "hudor" meaning "water". In biochemistry, hydratase refers to an enzyme that catalyzes the addition of water to a molecule.

Therefore, "aconitate hydratase" refers to an enzyme that is involved in the hydration (addition of water) of aconitate, a type of molecule found in biochemical pathways.