ACID THIOL LIGASES Meaning and
Definition
-
Acid thiol ligases are a type of enzyme that catalyze the formation of covalent bonds between sulfur-containing molecules and other compounds through a process known as thiolation. Thiolation involves the transfer of a sulfur atom from a thiol (a compound containing a sulfhydryl group, -SH) to a substrate molecule.
These ligases are called acid thiol ligases because they function optimally under acidic conditions, typically in the pH range of 5 to 6. They are often involved in important cellular processes such as the synthesis of coenzyme A, a molecule that plays a critical role in metabolism. Acid thiol ligases specifically catalyze the attachment of a thiol group to the 4'-phosphopantetheine moiety of apo-acyl carrier protein (ACP), ultimately leading to the formation of holo-ACP.
The holo-ACP molecule is essential for fatty acid biosynthesis, as it acts as a carrier to transport intermediates in the fatty acid synthesis pathway. Acid thiol ligases play a crucial role in this process by attaching the necessary thiol group to ACP, allowing it to interact with the other enzymes involved in fatty acid synthesis.
Overall, acid thiol ligases are enzymes that facilitate the attachment of sulfur-containing molecules to other compounds, particularly in the context of fatty acid biosynthesis. Their activity is optimal under acidic conditions, and they are essential for important cellular processes that rely on the covalent modification of proteins.
Common Misspellings for ACID THIOL LIGASES
- zcid thiol ligases
- scid thiol ligases
- wcid thiol ligases
- qcid thiol ligases
- axid thiol ligases
- avid thiol ligases
- afid thiol ligases
- adid thiol ligases
- acud thiol ligases
- acjd thiol ligases
- ackd thiol ligases
- acod thiol ligases
- ac9d thiol ligases
- ac8d thiol ligases
- acis thiol ligases
- acix thiol ligases
- acic thiol ligases
- acif thiol ligases
- acir thiol ligases
- acie thiol ligases
Infographic
Add the infographic to your website:
