The spelling of the word "achromacyte" can be explained through its phonetic transcription: /eɪˈkrəʊməsaɪt/. The first syllable, "a" is pronounced like "ay", the "chro" is pronounced like "kro", and the final syllable "cyte" is pronounced like "sight". This word refers to a colourless or white blood cell, and is made up of the prefix "a-" meaning "without", "chroma" meaning "colour", and "cyte" meaning "cell". The spelling may seem complex, but understanding its phonetic components can make it easier to pronounce and remember.
An achromacyte refers to a specialized type of blood cell characterized by the absence of color or pigment. These cells are also commonly known as achromatic or ghost cells. Achromacytes are formed due to the destruction or loss of hemoglobin, the iron-containing protein responsible for giving red blood cells their vibrant color.
Typically, achromacytes are found in conditions such as intravascular hemolysis, which occurs when red blood cells break down within the bloodstream. This can be caused by various factors, including immune-mediated responses, certain infections, or intrinsic abnormalities within the red blood cells themselves. As a result, the affected red blood cells lose their typical red color and become achromatic or transparent in appearance.
Microscopically, achromacytes are identifiable by their distinct lack of color when viewed under a microscope. Instead of the characteristic red hue, achromacytes appear pale and translucent. Their ghostly appearance indicates the absence or significant reduction of hemoglobin, resulting in impaired oxygen-carrying capacity and potential complications related to decreased oxygen delivery to the body's tissues.
Clinically, the presence of achromacytes in a blood sample can help diagnose and monitor certain conditions associated with intravascular hemolysis. Their identification through microscopic examination plays a crucial role in identifying hemolytic anemias and determining the severity of red blood cell destruction. Furthermore, it aids in assessing the effectiveness of treatment interventions and guiding subsequent management strategies.
Achromatocyte.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.