How Do You Spell ACETOLACTATE SYNTHETASE?

Pronunciation: [ˌasɪtəlˈakte͡ɪt sˈɪnθɪtˌe͡ɪs] (IPA)

The word "Acetolactate Synthetase" is spelled /əˌsitəʊˈlækteɪt sɪnθəˌteɪs/. The first syllable "ace-" is pronounced /əs/ as in "ace" or "base". The second syllable "to" is pronounced /təʊ/ like the number "two". The third syllable "-lactate" is pronounced /ˈlækteɪt/ as in "lactic acid". The final syllable "synthetase" is pronounced /ˈsɪnθəˌteɪs/, with the stress on the second syllable, and the "th" pronounced as in "think". This word refers to an enzyme that is involved in the biosynthesis of certain amino acids.

ACETOLACTATE SYNTHETASE Meaning and Definition

1. Acetolactate synthetase is an enzyme that plays a crucial role in the biosynthesis of branched-chain amino acids (BCAAs) in bacteria, plants, and fungi. It catalyzes the conversion of pyruvate, a key intermediate of the glycolytic pathway, into acetolactate, an important precursor in the production of BCAAs such as valine, leucine, and isoleucine.

   The acetolactate synthetase enzyme is part of the larger family of transferases, specifically classified as a pyruvate carboxylase-like enzyme. It requires the presence of ATP and Mg2+ ions as cofactors to catalyze the transfer of a carboxyl group from pyruvate to another molecule. The final product, acetolactate, is subsequently converted into other intermediates through additional enzymatic reactions to produce the desired BCAAs.

   This enzyme is highly conserved across different organisms, indicating its importance in cellular metabolism and the production of essential amino acids. Its activity is tightly regulated to ensure proper control of BCAA synthesis. Inhibition of acetolactate synthetase can be an effective strategy for the development of antimicrobial agents or herbicides, as it disrupts the growth and survival of bacteria and plants that rely on BCAA biosynthesis.

   In summary, acetolactate synthetase is an enzyme involved in the synthesis of branched-chain amino acids by catalyzing the conversion of pyruvate into acetolactate. Its role in cellular metabolism makes it an attractive target for the development of pharmaceutical drugs and herbicides.

Common Misspellings for ACETOLACTATE SYNTHETASE

• zcetolactate synthetase
• scetolactate synthetase
• wcetolactate synthetase
• qcetolactate synthetase
• axetolactate synthetase
• avetolactate synthetase
• afetolactate synthetase
• adetolactate synthetase
• acwtolactate synthetase
• acstolactate synthetase
• acdtolactate synthetase
• acrtolactate synthetase
• ac4tolactate synthetase
• ac3tolactate synthetase
• acerolactate synthetase
• acefolactate synthetase
• acegolactate synthetase
• aceyolactate synthetase
• ace6olactate synthetase
• ace5olactate synthetase

Etymology of ACETOLACTATE SYNTHETASE

The word "acetolactate" is derived from "acet-" (related to acetyl, a chemical group composed of two carbon and three hydrogen atoms), and "lactate" (a salt or ester of lactic acid). "Synthetase" is derived from "synthesis" (the combination of elements to form a whole) and the suffix "-ase" (used to denote an enzyme). Therefore, "acetolactate synthetase" refers to an enzyme involved in the synthesis of acetolactate.