The ABO Factor is a blood group classification system that refers to the presence or absence of specific antigens on the surface of red blood cells. The spelling of "ABO factor" is pronounced as /ˈeɪ.bəʊ/ /'fæk.tər/, using the International Phonetic Alphabet (IPA) symbols. The first syllable "A" is pronounced with an /eɪ/ sound, while the second syllable, "BO," is pronounced with a long /oʊ/ sound. The last syllable, "factor," is pronounced with the /æ/ and /tər/ sounds.
The ABO factor is a term used in human blood typing to categorize individuals based on the presence or absence of certain antigens on the surface of red blood cells. It refers to the classification system consisting of four main blood types: A, B, AB, and O, which are determined by the presence of specific antigens (A or B) on the red blood cell membrane or the absence of both (O). The ABO factor is hereditary and is determined by two genes, one inherited from each parent.
Individuals with blood type A have A antigens on the red blood cell surface, individuals with blood type B have B antigens, those with blood type AB have both A and B antigens, and those with blood type O have neither A nor B antigens. The presence or absence of these antigens is crucial in blood transfusions to avoid incompatible blood types, as the immune system may recognize transfused red blood cells as foreign and trigger an immune response.
In addition to the ABO factor, the Rh factor is also considered in blood typing. The Rh factor refers to another antigen, the RhD antigen, which can be either positive or negative. A combination of the ABO and Rh factors results in the different blood types, such as A positive, B negative, AB positive, and O negative, amongst others. The ABO factor is a fundamental component of blood compatibility and plays a vital role in determining the compatibility of blood transfusions and the possibility of hemolytic disease in newborns.
The term "ABO factor" refers to the blood group system that categorizes human blood into four types: A, B, AB, and O. The etymology of the term can be traced back to the early 20th century when the Austrian biologist and physician Karl Landsteiner discovered the presence of antigens on the surface of red blood cells.
The "ABO" in "ABO factor" stands for Landsteiner's initial findings, as ABO represents the first letters of the three major blood types he identified – A, B, and O. Landsteiner initially classified blood into three groups based on the presence or absence of these antigens. Later, the AB group was discovered when it was found that some individuals had both A and B antigens on their red blood cells.